Approach to the functionalized cyclopentane core of marine prostanoids by applying a radical cyclization of β-disubstituted acrylates.
نویسندگان
چکیده
A synthetic approach to highly functionalized cyclopentanes that incorporate adjacent secondary and tertiary alcohols is described. These systems, prepared in one step by a ketyl radical cyclization of β-disubstituted acrylates, represent the core of the marine prostanoid family of natural products.
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 11 36 شماره
صفحات -
تاریخ انتشار 2013